Some people who have been on the same antidepressant for years may find that it suddenly stops working. Identifying the right solution can be difficult and largely trial-and-error: Some patients may need a higher dose of the same medication, while others may need to try a new drug or a new combination of drugs, doctors say.
Our medical director, Dr. Salcedo, is consulted in this article on reasons why people may need to try other options to impact their symptoms. She suggests that increased stress may contribute, and offers additional ideas including therapy and supplemental medications that can help the patient.
Read more here: Wall Street Journal: Why Your Antidepressants Seem to Stop Working and What to Do About It